Formic Acid
Formic acid (HCOOH) is naturally-occurring, flammable, corrosive, organic, and the simplest carboxylic acid. Used as a hydride ion source in synthetic organic chemistry, a mobile phase component in HPLC, a preservative/antibacterial agent in agriculture, etc.
Formic or methanoic acid (CAS: 64-18-6; PubChem ID: 284) is a colorless organic acid with the formula HCOOH. At ambient temperatures, it has a strong, penetrating odor, like acetic acid. Used in chemical synthesis as an intermediate, this simple carboxylic acid is miscible in water and most organic solvents and is somewhat hydrocarbon-soluble.
Formic acid occurs naturally in the venom of some ants and bees. Formate, the conjugate base of formic acid, also occurs naturally in bodily fluids following methanol poisoning.
Formic acid is a source of hydride ion in synthetic organic chemistry, as in the Eschweiler-Clarke and Leuckart-Wallach reactions. It is also a useful component of the mobile phase in reversed-phase high-performance liquid chromatography (RP-HPLC) for peptides, proteins, and intact viruses.
Although formic acid is easily metabolized and eliminated, it can have toxic effects. Methanol metabolism produces formic acid and formaldehyde, which are responsible for the optic nerve damage that results from methanol poisoning. Chronic exposure in humans may cause kidney damage and skin allergies in some people.
In diluted forms, formic acid and formate esters are used as artificial flavorings and perfume additives. In higher concentrations, formic acid is flammable, and skin and eye contact with concentrated liquid or vapors is dangerous.
In agriculture, formic acid is used as a preservative and antibacterial agent and by beekeepers to kill mites. It is useful in leather tanning, textile dyeing and finishing, and in rubber production. Formic acid replaces mineral acids in limescale removers and other cleaning products.
Medchemexpress LLC SLB1122168 formic | C23H37N3O3 | 100 MG
SLB1122168 formic is a potent Spns2-mediated S1P release inhibitor with an IC50 of 94 nM. It is intended for research use only and not for patient administration.
- Potent Spns2-mediated S1P release inhibitor
- Inhibitor with an IC50 of 94 nM
- Intended for research use
Sigma Aldrich Fine Chemicals Biosciences SIGMA ALDRICH FINE CHEMICALS BIOSCIENCES
NC3982132 FORMIC ACID 98-100 FOR HPLC L
Sigma Aldrich Fine Chemicals Biosciences Formic acid | 64-18-6 | MFCD00003297 | 100mL
Formic acid | Purity: ≥88% | MW:46.03 | 64-18-6 | MFCD00003297 | 100mL
Sigma Aldrich Fine Chemicals Biosciences Formic acid, 64-18-6, MFCD00003297, 1 L
Linear Formula: HCOOH, Molecular Weight: 46.03, reagent grade, ≥95%.
Sigma Aldrich Fine Chemicals Biosciences Formic acid ACS reagent, >=88% | 64-18-6 | MFCD00003297 | 2.5L
Formic acid ACS reagent, >=88% | Purity: >=88% | Mol Wt: 46.03 | 64-18-6 | MFCD00003297 | 2.5L
Sigma Aldrich Fine Chemicals Biosciences Formic acid puriss. p.a., ACS reagent, reag. Ph. Eur., >=98% | 64-18-6 | MFCD00003297 | 500ML
Formic acid puriss. p.a., ACS reagent, reag. Ph. Eur., >=98% | Purity: >=98% | Mol Wt: 46.03 | 64-18-6 | MFCD00003297 | 500ML
Sigma Aldrich Fine Chemicals Biosciences Formic acid >=95%, FCC, FG | 64-18-6 | MFCD00003297 | 10KG
Formic acid >=95%, FCC, FG | Purity: >=95% | Mol Wt: 46.03 | 64-18-6 | MFCD00003297 | 10KG
Medchemexpress LLC Zelavespib formic (PU-H71) | 00-00-0 | 97.4% | 558.39 g/mol | C19H23IN6O4S | 5 MG
Zelavespib formic is a research-grade small-molecule inhibitor of heat shock protein 90 (Hsp90), supplied as a formic acid salt for laboratory studies. It is intended for in vitro and preclinical research use only.
- Potent Hsp90 inhibitor (IC50 51 nM in MDA-MB-468 cells).
- Formic acid salt suitable for biological assays.
- Available as solid and as a 10 mM solution in DMSO.
- High purity (97.39%).
- Molecular weight 558.39 g/mol; formula C19H23IN6O4S.
- For research use only; not for human or clinical use.
Medchemexpress LLC CBI1 formic | 461.40 | 50 MG
CBI1 formic is a covalent BAX inhibitor that selectively derivatizes BAX at C126. It inhibits BAX activation by triggering ligands or point mutagenesis, and also blocks t-2-hex lipidation and oligomerization of BAX. CBI1 formic is effective in inhibiting BAX activation induced by BH3 ligands, F116A mutagenesis or t-2-hex.
- Covalent BAX inhibitor
- Selectively derivatizes BAX at C126
- Inhibits BAX activation by triggering ligands or point mutagenesis
- Blocks t-2-hex lipidation and oligomerization of BAX
- Inhibits BAX activation induced by BH3 ligands, F116A mutagenesis or t-2-hex
- Available in 50 mg quantity
Medchemexpress LLC OAB-14 | 2140911-49-3 | 99.2% | 518.73 | 1 ML
OAB-14 is a derivative of Bexarotene that improves Alzheimer's disease-related pathologies and cognitive impairments. It works by increasing β-amyloid clearance and ameliorating the dysfunction of the endosomal-autophagic-lysosomal pathway in APP/PS1 transgenic mice. OAB-14 has no significant effect on body weight or liver toxicity after acute and chronic treatment.
- Improves Alzheimer's disease-related pathologies and cognitive impairments
- Increases β-amyloid clearance
- Ameliorates dysfunction of the endosomal-autophagic-lysosomal pathway
- Promotes microglia phagocytosis
- Attenuates downstream pathological events of Aβ accumulation
- Restores autophagy flux via the AMPK/mTOR pathway
- Enhances lysosomal activity and reduces Aβ accumulation in lysosomes
eMolecules 64-18-6 | Formic Acid, ACS Grade | Oakwood Chemical | MFCD00003297 | 46.025 | CH2O2 | 88.000 | OC=O | 1kg | 736631842
Formic Acid, ACS Grade | Oakwood Chemical | 64-18-6 | MFCD00003297 | 46.025 | CH2O2 | 88.000 | OC=O | 1kg | 736631842
Sigma Aldrich Fine Chemicals Biosciences Formic acid ACS reagent, >=88% | 64-18-6 | MFCD00003297 | 4X2.5L
Formic acid ACS reagent, >=88% | Purity: >=88% | Mol Wt: 46.03 | 64-18-6 | MFCD00003297 | 4X2.5L